REMODELING OF THE ACTIN NETWORK ASSOCIATED WITH THE NON-STRUCTURAL PROTEIN 1 (NS1) OF WEST NILE VIRUS AND FORMATION OF NS1-CONTAINING TUNNELING NANOTUBES

The cellular response to the recombinant NS1 protein of West Nile virus (NS1WNV) was studied using three different cell types: Vero E6 simian epithelial cells, SH-SY5Y human Training Pants neuroblastoma cells, and U-87MG human astrocytoma cells.Cells were exposed to two different forms of NS1WNV: (i) the exogenous secreted form, sNS1WNV, added to t

Abstract Background Intertumoral heterogeneity represents a significant hurdle to identifying optimized targeted therapies in gastric cancer (GC).To realize precision medicine for GC patients, an actionable gene alteration-based molecular classification that directly associates GCs with targeted therapies is needed.Methods A total of 207 Japanese p

Aquaponics is an agricultural practice incorporating aquaculture and hydroponic principles.This study assesses the current system design and production practices of the aquaponic industry, compares these metrics by stakeholder group, identifies trends, and provides recommendations for future development.An electronic survey of aquaponic stakeholder